Call 413.540.1234 to
schedule an appointment
CONCERN/EAP: 413.534.2625
Billing questions? Call: 413.540.1212
CRISIS: 413.733.6661

Alzheimers Disease and other Cognitive Disorders
Resources
Basic Information
Introduction & Causes of Cognitive DisordersDementiaAlzheimer's DiseaseOther Cognitive DisordersDementia Coping Skills & Behavior ManagementTraumatic Brain Injury (TBI)Conclusion and Resources
More InformationLatest News
Alzheimer's Disease Variants Linked to Brain AmyloidosisIdalopirdine May Not Improve Cognition in Mild Alzheimer'sHealth Tip: Alzheimer's and the HolidaysRheumatic Diseases Associated With Increased Dementia RiskNo Magic Bullet for Preventing Late-Life DementiaDementia May Be More Common in Rural AreasThere's Still No Proven Way to Prevent Alzheimer'sHealth Tip: Make Your Home Safer For People With Alzheimer'sAs Hearing Fades With Age, Dementia Risk May RiseAlzheimer's Cases to Double by 2060: ReportGene Discovery May Help Fight Alzheimer'sMemory Scores Limited As Alzheimer's Screening ToolMagnesium Boosts Environmental Enrichment in Alzheimer'sCould New 'Brain Training' Program Help Prevent Dementia?Millions Could Miss Out on a Potential Alzheimer's BreakthroughSleep Apnea May Boost Alzheimer's RiskNew Finding Hints at Clue to DementiaResilient Brain Connections May Help Against Alzheimer'sAmerica's Dementia Caregivers Cite Stresses, RewardsHealth Tip: Identifying Vascular DementiaOne Type of Dementia Is Especially CostlyA More Accurate Predictor for Alzheimer's?Failing Sense of Smell Tied to Dementia RiskMagnesium Levels Tied to Dementia RiskIs Dementia Declining Among Older Americans?Intracranial Pressure Monitoring No Benefit in Pediatric TBIGender-Specific High-Risk 'Window' Seen in Alzheimer'sWomen at Risk for Alzheimer's Face Critical 10-Year Window, Study SaysDo Fewer Nightly Dreams Mean Higher Dementia Risk in Seniors?Dementia Care: A Huge Financial Burden for U.S. FamiliesPopular Heartburn Drugs Don't Raise Risk of Alzheimer's: StudyFamilies Shoulder Majority of Costs Related to Dementia CareMidlife Vascular Risk Factors Tied to Increased Risk of DementiaBlood Pressure Fluctuations Tied to Dementia Risk in StudyMidlife Behaviors May Affect Your Dementia RiskTraveling With Dementia: Tips for Family CaregiversHigher Risk of Dementia Seen in Those Hailing From 'Stroke Belt'Health Tip: Alzheimer's Affects SleepIncreased Dementia Risk With Hearing Loss in Older AdultsNoninvasive Brain Test May Pinpoint Type of DementiaTargeting 9 Risk Factors Could Prevent 1 in 3 Dementia Cases: StudyAAIC: Rx + Training Shows Benefit in Advanced Alzheimer'sAAIC: Alzheimer Biomarkers Up With Sleep Disordered BreathingDozens of Potential Alzheimer's Meds in the PipelineSpecial Training Plus Medication Might Help People With Advanced Alzheimer'sOne Social Hour a Week Can Help Someone With DementiaSleep Problems: An Early Warning Sign of Alzheimer's?Severe Head Injury May Raise Dementia Risk Years LaterPPIs Not Found to Raise Risk of Alzheimer's DiseasePopular Heartburn Meds Don't Raise Alzheimer's Risk: Study
Questions and AnswersLinksBook Reviews
Related Topics

Aging & Geriatrics
Memory Problems
Elder Care

PPIs Not Found to Raise Risk of Alzheimer's Disease


HealthDay News
Updated: Jun 28th 2017

new article illustration

WEDNESDAY, June 28, 2017 (HealthDay News) -- Proton pump inhibitors (PPIs) don't appear to increase the risk of dementia, as has been previously suspected, according to a study published online June 7 in the Journal of the American Geriatrics Society.

Noting that previous studies have suggested PPIs may increase the risk of dementia and Alzheimer's disease in people aged 75 and older, a team of researchers from Emory University in Atlanta analyzed data from the National Alzheimer's Coordinating Center. The data, compiled from 2005 to 2015, included 10,486 Americans, aged 50 or older, with normal brain function or mild cognitive difficulties.

The team found that 8.4 percent always used PPIs, and 18.4 percent sometimes did. Users were older than non-users. Those who used PPIs were at a lower risk of a decline in cognitive skills. However, those who used PPIs were also more likely to use anticholinergic medicines that have been linked to cognitive difficulties. The investigators also found that PPI users were more likely to have experienced cardiovascular disease, depression, diabetes, hypertension, stroke, or transient ischemic attacks.

"PPIs were not associated with greater risk of dementia or of Alzheimer's disease, in contrast to recent reports. Study limitations include reliance on self-reported PPI use and lack of dispensing data," the authors write. "Prospective studies are needed to confirm these results to guide empirically-based clinical treatment recommendations."

Abstract
Full Text