Call 413.540.1234 to
schedule an appointment
CONCERN/EAP: 413.534.2625
Billing questions? Call: 413.540.1212
CRISIS: 413.733.6661

Drug Addiction
Resources
Basic InformationLatest News
Vets Who Get Opioids From VA, Medicare at Higher Overdose RiskAHA News: Opioid Crisis Brings Concerns About Heart DangersAnother Side Effect of the Opioid Crisis: Heart InfectionsU.S. Deaths From Suicide, Substance Abuse Reach Record HighOpioid Overdose Deaths Quadruple, Centered in 8 StatesKratom-Related Poisonings Are Soaring, Study FindsFDA Fell Short in Preventing Fentanyl Abuse Crisis, Report ClaimsMore Car Crashes Tied to Drivers High on OpioidsInsurers Making It Harder to Treat Opioid Addiction: StudyMeth Abuse Driving Big Spike in Syphilis CasesPoor Whites Bear the Brunt of U.S. Opioid Crisis, Studies FindOpioid OD Deaths Are Saving Lives Through TransplantationMaking OxyContin 'Tamper Proof' Helped Spread Hepatitis CAHA: Marijuana, Cocaine May Play Role in Young Americans' Rising Stroke RateAnother Opioid Scourge: Infection-Related StrokesOpioid Danger to Newborns Varies By RegionAs More Smoke Pot, Are Their Jobs at Risk?Big Pharma's Marketing to Docs Helped Trigger Opioid Crisis: StudyMore Americans Mixing Opioids With SedativesOpioids Now More Deadly for Americans Than Traffic AccidentsFatal Drug ODs Soaring Among Middle-Aged Women: CDCPostpartum Opioid Rx May Lead to Persistent Use: StudyOpioid Overdose Deaths Triple Among Teens, KidsMore Evidence That Abuse of Xanax, Valium Is on the RiseCould Pot Harm Men's Sperm?Opioids May Help Chronic Pain, But Not MuchFentanyl Now the No. 1 Opioid OD KillerNew Approach to Opioid Crisis: Supervised Heroin Injection Programs?Opioids Plus Other Drugs a Deadly Mix for Heavy UsersEven Wisdom Tooth Removal May Spur Opioid AddictionMeth, Opioid Use in Pregnancy on the RiseOpioids Increasingly Tied to Deaths of Pregnant WomenMany Drugstores Won't Dispense Opioid Antidote as RequiredAHA: Meth Use Producing Younger, Harder-to-Treat Heart Failure PatientsOver 2 Million Americans Have Hepatitis C; Opioids Help Drive SpreadMany Young Drug Abusers Not Tested for Hepatitis C, Study FindsCoffee Shop Workers on Front Lines of Opioid CrisisReports Warn of Growing Opioid Crisis Among Seniors'No Documented Reason' for 1 in 3 Outpatient Opioid Rxs: StudyStates Struggle With Onslaught of Opioid OD DeathsU.S. Deaths From Suicide, Drugs Surpass DiabetesDoctors Write Fewer Opioid Scripts After Learning of Overdose DeathNumber of Opioid-Addicted Women Giving Birth QuadruplesAs Opioid Epidemic Rages, Painkiller Prescriptions Don't DropFDA Warns of Deaths Tied to Tainted Synthetic PotEven Once-a-Week Pot Smokers Have More Cough, PhlegmDeath Certificate Data May Miss Many Opioid ODs: StudyKids Are Overdosing on Med Meant to Fight Opioid AddictionHave Insurers Played a Role in Opioid Crisis?If Opioid Addicts Survive OD, Other Hazards Lie Ahead: Study
Links

Substance Use Disorders Linked to Conversion to Schizophrenia


HealthDay News
Updated: Apr 26th 2018

new article illustration

THURSDAY, April 26, 2018 (HealthDay News) -- Substance use disorders are associated with conversion from schizotypal disorder to schizophrenia, according to a study published online April 25 in JAMA Psychiatry.

Carsten Hjorthøj, Ph.D., from Copenhagen University Hospital in Denmark, and colleagues conducted a prospective cohort study which included a population-based sample of 2,539 individuals born in Denmark with an incident diagnosis of schizotypal disorder and without a previous diagnosis of schizophrenia.

The researchers found that 16.3 percent of the study participants experienced conversion to schizophrenia after two years. After 20 years, the conversion rate was 33.1 and 58.2 percent overall and among those with cannabis use disorders, respectively. Any substance use disorder was correlated with conversion to schizophrenia in fully-adjusted models (hazard ratio, 1.34). On stratification by substance, there were correlations for conversion to schizophrenia for cannabis use disorders, amphetamine use disorders, and opioid use disorders (hazard ratios, 1.3, 1.9, and 2.74, respectively). Concurrent use of antipsychotics, functional level before incident schizotypal disorder, or parental history of mental disorders did not explain these correlations.

"Conversion rates are high even in those without substance use disorders, indicating a need for universal and substance-targeted prevention in individuals with schizotypal disorder," the authors write.

Abstract/Full Text